THE DEFINITIVE GUIDE TO LSD CRYSTAL

From the LSD-certain crystal structure, the aspect chain on the lid residue L209EL2 forms substantial hydrophobic contacts with the two LSD and bordering residues in TMs III, IV, and V (Figure 4C). When the lid moved aside to reveal the binding pocket in simulation, numerous of such contacts broke. We Hence hypothesized that L209EL2 functions as be